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                                  README
                             StackPACK v2.2.1

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Release date: February 2003

This version of stackPACK replaces stackPACK v2.1.1 for HP Tru64 only 
and includes many new feature requests from customers. StackPACK 
v2.2.1 for HP Tru64 has the same functionality as stackPACK v2.2 for 
Intel-based PC Linux Red Hat, Silicon Graphics Irix, and Sun Solaris, 
and is a special release to accommodate many Tru64-specific issues 
that were encountered during development. 

StackPACK v2.2.1 contains significant improvements over stackPACK 
v2.1.1, and focuses mainly on increasing the accuracy of consensus 
sequences and improving the ability to handle large datasets. 
Enhancements made towards these goals include:

- The incremental addition of new data to existing clusters, 
  maintaining the cluster history.

- The inclusion of phred quality scores contributing to accurate 
  consensus sequence generation.

- The ability to assemble and generate consensus sequences with 
  original unmasked data, whilst still retaining the benefits of 
  accurate clustering using masked data.

In addition continued improvements in terms of parameterization, data 
management,viewing, and extraction functions enable more rapid 
assessment and manipulation of alignments and alignment analyses. 
Please refer to the release notes for a comprehensive summary of all 
new features and improvements in this release.

Several documentation files exist for this release:
- README	     this file
- Release_Notes	     details about the release including updates, new 
                     features and known problems
- Install_New 	     installation instructions
- Install_Update     instructions for updating an existing stackPACK
                     installation

We hope that the stackPACK transcript reconstruction and variation 
analysis tools prove valuable to your research efforts and that the 
incremental addition of new data to existing clusters enhances the 
utility of stackPACK.

Your feedback is very important to us, and any comments or suggestions
for improvement can be mailed to the stackPACK production team:
support@egenetics.com    


Sincerely

Liza Groenewald
Product Manager